Infections in hospitalized patients may originate from their own bacteria. Hospitals implement strict hygiene and sanitation protocols to shield vulnerable patients with serious illnesses from bacteria that can be lethal, despite rarely affecting healthy individuals. Despite intensive infection-con
The researchers found that even when no bacteria are present in the bladder, urinary tract infections can still develop after the insertion of sterile tubes, known as catheters, into the urinary tract.Hospitals implement strict hygiene and sanitation protocols to shield vulnerable patients with serious illnesses from bacteria that can be lethal, despite rarely affecting healthy individuals.
Feldman teamed up with co-senior author Scott J. Hultgren, Ph.D., the Helen L. Stoever Professor of Molecular Microbiology and an expert on UTIs, to investigate why so manyMost UTIs among otherwise healthy people are caused by the bacteriumcan hide out in bladder cells for months after a UTI seems to have been cured, and then re-emerge to cause another infection.
Feldman and Hultgren — along with co-first authors Jennie E. Hazen, a graduate student, and Gisela Di Venanzio, Ph.D., an instructor in molecular microbiology — investigated whetherA. baumanniiA. baumanniiOnce the infections had resolved and no bacteria were detected in the mice’s urine for two months, the researchers inserted catheters into the mice’s urinary tracts with a sterile technique.
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