And they might give a big boost to a new drug. 💊
Earlier this week, the Food and Drug Administration approved the first treatment in nearly 20 years for Alzheimer's disease but the drug's effectiveness will likely see some controversy, since further clinical trials are needed.
And, most crucial: the drug and ultrasound therapy both show signs of restoring memory-forming abilities in humans.published an initial study that saw ultrasound waves successfully remove beta-amyloid from the brains of mice. Beta-amyloids are a special class of proteins linked to several symptoms in people with Alzheimer's, including dementia and cognitive decline. And the researchers found that scans of the brain in ultrasound help to break up beta-amyloid, reversing the process of neurological damage caused by the amyloids.
More specifically, the ultrasound, when combined with intravenously injected microbubbles, allows the a relaxing of the blood-brain barrier, activating"dormant microglia which then take up the amyloid into their lysosomes where it is digested," explained Götz, in the email."We have shown that tau is cleared by a second mechanism, neuronal autophagy. When microbubbles are not overdosed the procedure is safe.
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