Joshua Cohen covers healthcare policy, with a special focus on prescription drug pricing and reimbursement. Cohen writes about a wide variety of topics, including weight loss drugs, the Inflation Reduction Act, and even things like health risks related to climate change.
July 2024. The U.K. regulatory authority followed suit in Oct. 2024. However, the cost-effectiveness watchdog the National Institute for Health and Care Excellent says that donanemab is not cost-effective. last week for certain patients. This follows the Unites States Food and Drug Administration granting marketing authorization in July of this year. However, in the U.K.
Donanemab works by removing a sticky protein, beta amyloid plaque, from the brain. Such plaque build-up is hypothesized to be a cause of Alzheimer's disease. Tau plaque is also thought to contribute to Alzheimer’s disease. And in a phase 3 trial, Kisunla was shown to be effective atAmong 1,700 trial participants with early symptomatic Alzheimer’s disease and amyloid and tau pathology, donanemab slowed the rates of cognitive and functional decline.
The U.S. situation is quite different. There is no single payer or NICE informing decisions by a lone government insurer. Generally, payers in both the public markets, such as Medicare and Medicaid, as well as insurers in the commercial sector, each make coverage decisions.
Aduhelm Tau Beta Amyloid Plaque Alzheimer's Disease NICE Cost-Effectiveness ARIA
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