The United Kingdom is reviewing diabetes and weight-loss drugs after reports of self-harming thoughts.
LONDON, United Kingdom – Britain is reviewing a class of drugs used in a diabetes medicine and a weight-loss treatment sold by Novo Nordisk NOVOb.CO after some patients reported suicidal or self-harming thoughts, two weeks after similar action by the European Union.
It also includes Novo’s Saxenda, which contains the active ingredient liraglutide and is approved as a weight-loss treatment. Saxenda is Novo’s older GLP-1 drug and has lower effectiveness than its newer obesity treatment Wegovy, which contains semaglutide. The MHRA said AstraZeneca’s GLP-1 drug for type 2 diabetes, called exenatide and marketed as Bydureon, was also included in the review. AstraZeneca did not immediately respond to a request for comment on Wednesday.
The MHRA told Reuters that its review was initiated on July 12. The agency said it could not specify when it would conclude or what the results might be. Between 2010 and July 6 this year, the MHRA received 12 suspected adverse drug reactions involving liraglutide also associated with “suicidal and self-injurious behaviour”.
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