An 8-week methylation-supportive diet and lifestyle program was found to significantly decrease biological age in a case series of women, suggesting that such interventions may affect underlying mechanisms of aging rather than disease-driven aging, and be effective for both sexes. A new research
The data suggest “that a methylation-supportive diet and lifestyle intervention may favorably influence biological age in both sexes during middle age and older.”
A case series of six women who underwent a methylation-supportive diet and lifestyle program, aimed at affectingmethylation and measures of biological aging, was reported on by researchers Kara N. Fitzgerald, Tish Campbell, Suzanne Makarem, and Romilly Hodges. These researchers are associated with the Institute for Functional Medicine, Virginia Commonwealth University, and the American Nutrition Association.
The team carried out an intervention consisting of an eight-week program. This program included guidance on diet, sleep, exercise, and relaxation, supplemental probiotics and phytonutrients, and nutritional coaching. DNA methylation and biological age analysis , normalized using the SeSAMe pipeline) were conducted on blood samples at baseline and at the end of the eight-week period.
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