Researchers at the Tufts Lyme Disease Initiative recently received grants totaling more than $7 million to build on an already impressive array of discoveries that Tufts' teams have made to combat tick-borne diseases.
While Lyme disease can often be successfully treated with antibiotics, 10-20% of patients experience persistent fatigue, joint pain, and mental impairments that last months or years. For some, it is never clear whether symptoms signal persistent infection, reinfection, or malfunction by the body's immune system.
Along with Samuel Telford III, a professor in the Department of Infectious Disease and Global Health at Cummings School of Veterinary Medicine, Hu and other colleagues also received an $885,000 grant from Tarsus Pharmaceuticals to help develop an oral drug that could be used to kill ticks that are feeding on humans, thereby preventing transmission of Lyme disease.
Related StoriesTanja Petnicki-Ocwieja, a research assistant professor in molecular biology and microbiology at the School of Medicine, is studying another facet of an altered immune response that may trigger persistent symptoms. Like Strle, her efforts may help scientists better understand both chronic Lyme and long COVID.
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