Old lipid drug holds new promise for reducing the need for retinal laser or intravitreal injections.
in people with early retinal changes, with the potential to reduce the need for retinal laser or intravitreal injection treatment, new trial data suggest. trial of more than 1100 people randomly assigned to fenofibrate or placebo for 4 years, fenofibrate led to a 27% reduction in the progression of, or treatment for, diabetic retinopathy or maculopathy.
Results were similar for participants with type 1 and type 2 diabetes, and those with normal vs impaired renal function. There was no difference between groups in major cardiovascular events or nontraumatic lower limb amputations, and no effect on urinelower in the fenofibrate group on average throughout the study, a significant difference. But, Priess noted, this effect was reversible.
He added that his team will now follow eye and kidney function in these trial participants for the next 10 years.
Microvascular Complications Of Diabetes Retinal Disease Retinopathy Laser Laser Therapy Kidneys UK Site Content United Kingdom Site Content United Kingdom UK Vision Care And Maintenance UK National Health Service United Kingdom National Health Service UK NHS NHS National Health Service Diabetes Mellitus Type 2 Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM
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