How Huntington'sdisease affects different neurons MIT NatureComms
2.5, . Slices were allowed to recover for 1 h at room temperature post-slicing before recording commenced. When we performed whole-cell patch-clamp experiments accompanied by membrane break-through and intracellular dialysis, access resistance was measured every 1-2 min to ensure the quality of measurements. Only cells with initial Ra of 0.1, with FDR-adjustedWe used HALO to analyze data taken by TissueFAXS Whole Slide Scanning System from TissueGnostics .
To prepare for semi-automated image analysis, we exported all images taken by TissueFAXS systems in 16-bit format with the full range of bit color intensity values ., we applied customized algorithm modified from Indica_Labs_-FISHIF v2.1.5 to data from dorsal striatal regions . Briefly, we set a threshold to detect nuclei by using DAPI channel, and marked surrounding cytoplasm.
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