Tiny microlaser sensors offer supercharged biosensing

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Tiny microlaser sensors offer supercharged biosensing
MicroarraysWearable TechnologyOptics
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Researchers have developed a 3D micro-printed sensor for highly sensitive on-chip biosensing, opening new opportunities for developing high-performance, cost-effective lab-on-a-chip devices for early disease diagnosis.

Researchers have developed a 3D micro-printed sensor for highly sensitive on-chip biosensing. The sensor, which is based on a polymer whispering-gallery-mode microlaser, opens new opportunities for developing high-performance, cost-effective lab-on-a-chip devices for early disease diagnosis.

One challenge in using these sensors in real-life applications is that coupling light into them typically requires a tapered optical fiber with a diameter smaller than 2 microns. Such tiny fibers are difficult to align and susceptible to various environmental disturbances. This has posed a barrier to integrating such microlaser sensors into lab-on-a-chip devices for real-time, high-sensitivity detection of biomolecules.

Next, the researchers plan to integrate the microlaser sensors into a microfluidic chip to develop optofluidic biochips that could be used for rapid and quantitative detection of multiple disease biomarkers simultaneously.

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