In a small study, researchers modified patients’ immune cells to target their particular cancer—but it only worked for a third of volunteers.
step for Crispr, scientists have used the gene-editing tool to make personalized modifications to cancer patients’ immune cells to supercharge them against their tumors. In a small study published today in the, a US team showed that the approach was feasible and safe, but was successful only in a handful of patients.
“What we’re trying to do is really harness every patient’s tumor-specific mutations,” says Stefanie Mandl, chief scientific officer at Pact Pharma and an author on the study. The company worked with experts from the University of California, Los Angeles, the California Institute of Technology, and the nonprofit Institute for Systems Biology in Seattle to design the personalized therapies.
Scientists grew more of the edited cells, enough to constitute what they hoped would be a therapeutic dose. Then they infused the edited cells back into each of the volunteers, who had all previously been treated with several rounds of chemotherapy. The edited T cells traveled to the tumors and infiltrated them.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
23 Personalized Gifts That Go the Extra Mile and Show You CareWhether it's for your college bestie, lover, little sibling or colleague, we got you.
Read more »
Meet the Pieca: A Raspberry Pi Camera With a Leica M-MountA computer engineer has created what he calls the Pieca: a Raspberry Pi camera module with a Leica M-Mount fitted onto it.
Read more »
M6 Tebay Services' therapy garden given green lightA therapeutic garden beside a motorway services aims to boost volunteers' mental health.
Read more »
Gene Therapy Can Restore Night Vision After Decades of Congenital BlindnessThe patients had Leber Congenital Amaurosis, a type of genetic congenital blindness. According to researchers at the Scheie Eye Institute at the Perelman School of Medicine at the University of Pennsylvania, adults with a genetic form of childhood-onset blindness experienced remarkable recoveries o
Read more »
Enzyme treatment given directly to fetus prevents symptoms of rare genetic diseaseIn a medical first, researchers have delivered an enzyme into the womb to treat a fetus’ rare genetic disorder, helping head off heart and muscle defects.
Read more »
Find affordable, effective therapy for less with BetterHelp — save 25% nowEverybody needs some help sometimes.
Read more »