This May Be Why Women Are Far More Likely to Get Autoimmune Diseases

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This May Be Why Women Are Far More Likely to Get Autoimmune Diseases
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Nearly 80% of people who suffer from autoimmune diseases are women.

relate to the skin.) For this study, however, they analyzed genetic material from skin samples of 82 healthy men and women.

None of the participants had autoimmune diseases. Nevertheless, they did have some “striking differences in gene expression,” said first author Yun Liang, PhD, a dermatology research investigator, in the statement. In total, the researchers discoveredin women versus men. Many were already known to be involved in immune function, Liang added, and some have even been linked to autoimmune disease.

“This finding suggested that these sex-biased genes contributed to not only increased disease susceptibility but possibly also heightened disease activity,” the researchers wrote in their paper. “In this context, we note that being female is the strongest risk factor for the development of autoimmunity, and it dwarfs the identified autoimmune genetic risk variants.”

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