It turns out the appendix, as easy to dismiss as it is to remove, may have a vital purpose after all, including protecting us from gastrointestinal and other diseases.
When doctors and patients consider the appendix, it's often with urgency. In cases of appendicitis, the clock could be ticking down to a life-threatening burst. Thus, despite recentBut what if removing the appendix could raise the risk for gastrointestinal diseases like irritable bowel syndrome and colorectal cancer ? That's what some emerging science suggests. And though the research is early and mixed, it's enough to give some health professionals pause .
This safe house hypothesis could explain why the gut microbiome may be different in people who no longer have an appendix. In one smallThe appendix likely has a second function, too, Smith said: It may serve as a training camp for the immune system."When there is an invading pathogen in the gut, it helps the GI system to mount the immune response," she said. The human appendix is.
Why? According to Parker, appendectomy may work for ulcerative colitis because it's"a way of suppressing the immune system, especially in the lower intestinal areas." Afound that people who'd had their appendix removed before being diagnosed with ulcerative colitis were less likely to need their colon removed later on.that removing the appendix may reduce the numbers of certain immune cells called CD3+ and CD8+ T cells, causing a weakened immune surveillance.
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