The Neuroscience of Insatiable Hunger

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The Neuroscience of Insatiable Hunger
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This may be why some people can't tell when they're full and may overeat as a result, according to ckbergland

Based on previous research into Prader-Willi syndrome, Betley and Low began to speculate that the cerebellum might be playing a heretofore unknown role in insatiable hunger.

Holsen's previous research focused on neural mechanisms underlying hyperphagia in Prader‐Willi syndrome and looked at"subcortical foodcircuitry and prefrontal inhibitory circuitry functioning in response to food stimuli before and after eating." , Bentley describes this moment of discovery and initial skepticism about what they were seeing:"The cerebellum pops out, and we were all looking at this, saying, 'Is this real?' [It] was mind-blowing. In fact, it was so mind-blowing I thought it had to be wrong."

"It's amazing that you can still find areas of the brain that are important for basic survival behaviors that we had never before implicated. And these brain regions are important in robust ways," Betley noted.

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