Belgian researchers have proposed that a recent outbreak of mpox may have ended due to “network immunity.” The epidemic saw over 85,000 cases worldwide and affected men who have sex with men the most. The decline in the epidemic after July 2022 remains unclear, but the researchers suggest that the c
ore members of the sexual network being infected first generated “network immunity” that halted the epidemic.
Cases rose rapidly from May 2022, before starting to decline a few months later. The reasons the outbreak waned are unclear. The subsequent decline in the epidemic after July 2022 remains insufficiently explained. Possible explanations include improved awareness and behavioural change in the population at risk and acquisition of vaccination- or infection-induced immunity.
To find out more, they used two sets of data collected at the Institute of Tropical Medicine in 2022. All participants provided informed consent.Among the 155 individuals with mpox, 95.5% were gay and bisexual men who have sex with men and the median number of sexual partners in the previous three weeks was two.
For the purposes of the analysis the PrEP users were divided into two groups, core PrEP-users and non-core PrEP-users . A history of syphilis was used as a proxy for more risky sexual behaviour in the past: a person who had syphilis is probably more centrally located in the sexual network than someone who never had syphilis.
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