Newborn screening for neonatal vitamin B12 deficiency may lead to a fourfold reduction in chances of developing symptomatic vitamin B12 in the first year of life.
Newborn screening for neonatal vitamin B12 deficiency may lead to a fourfold reduction in chances of developing symptomatic vitamin B12 in the first year of life compared with infants without newborn screening , a hospital-based surveillance study in Germany indicates.
The researchers analyzed 61 cases of vitamin B12 deficiency reported to the German Pediatric Surveillance Unit. They were either identified by newborn screening or diagnosed after the onset of suggestive symptoms . The current study confirmed these reports and highlighted that the most common presentations in symptomatic infantile vitamin B12 deficiency were muscular hypotonia, anemia, developmental delay, malnutrition or failure to thrive, and microcephalia, brain atrophy, or delayed myelination.
Newborn Screening Vitamins Newborn Neonate Germany German Anemia Anaemia Children Child Childhood Pediatrics Kids Developmental Delay Megaloblastic Anemia Megaloblastic Anaemia
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