Here's what won the 2019 Nobel Prize in Medicine
. After studying medicine at Cambridge University and completing nephrology training at Oxford, he subsequently became the Nuffield Professor of Clinical Medicine at Oxford and the Director of Clinical Research at the Francis Crick Institute in London, Director for Target Discovery Institute at Oxford, a Member of the Ludwig Institute for Cancer Research, and knighted.
To understand the importance of their discoveries, it’s important to understand the how your body needs complex ways to regulate oxygen levels. As you first learn when you try to put a sock over your head , oxygen is pretty fundamental to everything that you do. Without it, the trillions and trillions of cells in your body couldn’t survive and function. Each cell uses oxygen to help break down nutrients into energy. Thus, no oxygen, no energy. No energy, no cells, and no you.
Therefore, like a well-run city, your body needs ways of sensing what’s going on in each of the neighborhoods and adjusting oxygen levels accordingly. One way of adjusting your body’s oxygen supply in general is by changing your breathing rate. The carotid arteries are the major blood vessels in your neck and the ones that often spurt blood in slasher horror movies. These arteries include structures called carotid bodies that can check the oxygen levels in the passing blood.
Experiments showed that when oxygen levels are high, cells have very low levels of HIF-1α because the HIF-1α that’s produced gets rapidly degraded. However, when oxygen levels dip low, HIF-1α, in the words of the Supremes, keeps on hanging on and doesn’t degrade as quickly. Therefore, there is more HIF-1α around to stimulate the EPO genes to produce more EPO.
William G Kaelin Jr., MD, speaks at the Dana Farber Cancer Institute on October 7, 2019 in Boston, Massachusetts. Here is an example of how starting on one path doesn’t necessarily lead you to where you thought you would go and how the most interesting things in life can be unexpected.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Kaelin, Ratcliffe and Semenza win 2019 Nobel Prize in MedicineScientists William Kaelin, Peter Ratcliffe and Gregg Semenza win Nobel prize for their work on cellular adaptation to fluctuating oxygen which paved the way for new strategies to fight anaemia and cancer
Read more »
The life-saving science behind the 2019 Nobel Prize for MedicineThe research could lead to new treatments for potentially deadly conditions including cancer, heart attack, and stroke. - NBCNewsMACH
Read more »
Three Astrophysicists Reveal Structure Of Universe To Win The 2019 Nobel PrizeJim Peebles, Michel Mayor and Didier Queloz just won the 2019 Nobel Prize in Physics. It couldn't be more well-deserved.
Read more »
Peebles, Mayor and Queloz win 2019 Nobel Prize for physicsScientists James Peebles, Michel Mayor and Didier Queloz won the 2019 Nobel Priz...
Read more »
Brothers Osborne to Receive Vanguard Award at 2019 ASCAP Country Music AwardsCountry duo Brothers Osborne will be honored with the Vanguard Award at ASCAP's Country Music Awards on Nov. 11 in Nashville.
Read more »
The Most Talked-About Celebrity Weddings of 2019 — So FarThe most talked-about celebrity weddings of 2019 — so far.
Read more »