Teva and Sanofi's Duvakitug Shows Promise in Phase 2 IBD Study

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Teva and Sanofi's Duvakitug Shows Promise in Phase 2 IBD Study
PharmaceuticalsUlcerative ColitisCrohns Disease
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Teva Pharmaceutical and Sanofi announced positive results from a Phase 2 study of duvakitug, a monoclonal antibody, for treating ulcerative colitis (UC) and Crohn's disease (CD). The study met its primary endpoints, with duvakitug demonstrating significant clinical remission and endoscopic response rates compared to placebo. The companies plan to progress to Phase 3 trials pending regulatory approvals.

Teva Pharmaceutical and Sanofi stocks were rising on Tuesday after the companies announced successful results of a phase 2 study involving the treatment of patients with ulcerative colitis and Crohn’s disease. The study investigated duvakitug, a human monoclonal antibody targeting, for the treatment of moderate-to-severe inflammatory bowel disease . UC and CD are the two main types of IBD .

“These unprecedented results show that duvakitug could represent the next frontier in treating ulcerative colitis and Crohn’s disease. If the magnitude of effect persists in the Phase 3 program, we believe we will have a differentiated medicine for IBD patients who are in urgent need of new options,” Houman Ashrafian, MD, PhD, executive vice president, head of R&D at Sanofi, said.

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