The sFlt-1/PlGF ratio did not effectively gauge future preeclampsia risk in pregnant patients with SLE and proteinuria.
WASHINGTON — A diagnostic test to predict preeclampsia does not effectively rule in or out this pregnancy complication in women with systemic lupus erythematosus and proteinuria, according to new research presented at the
The test is a ratio of two biomarkers that measure spiral artery and placental health: Soluble fms-like tyrosine kinase 1 and placental growth factor . In the general population, a sFlt-1/PlGF ratio ≤ 38 effectively rules out the short-term risk for preeclampsia, whereas a ratio ≥ 85 is moderately predictive of preeclampsia. However, it was not known how this test would fare in pregnant women with SLE who are already at a higher risk for the complication.
The analysis included 79 pregnancies, of which 30% developed preeclampsia. Nearly half of the participants identified as Black or African American. About 30% had a history of lupus nephritis, and half of these patients had active disease during their pregnancy. About half of the women reported that this was their first pregnancy, and an additional 17% of women reported a prior episode of preeclampsia.
Similar to the general population, sFlt-1/PlGF ≥ 85 was only moderately predictive of preeclampsia. Over half of all patients with this high ratio developed preeclampsia, but more than 40% did not.
Pregnant Pre-Eclampsia Preeclampsia Toxemia Of Pregnancy Toxaemia Of Pregnancy Systemic Lupus Erythematosus SLE - Systemic Lupus Erythematosus Systemic Lupus Erythaematosus SLE Proteinuria Lupus Lupus Nephritis Blood
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Yellowstone’s Beth Actor Kelly Reilly Gives Mixed Response To Season 6 & Spinoff ReportsKelly Reilly as Beth Dutton in Yellowstone season 5, episode 7
Read more »
What to do with Honeywell stock after its sharp post-earnings pullbackThe industrial giant reported mixed third-quarter results compounded by a mixed outlook.
Read more »
NBA's Anthony Edwards Demands DNA Test After Ayesha Howard Gives BirthMinnesota Timberwolves star Anthony Edwards requested a DNA test from Ayesha Howard the day after she gave birth to a baby girl
Read more »
Democrats Test ‘No Religious Test’ Clause in Attacks on Trump NomineesSource of breaking news and analysis, insightful commentary and original reporting, curated and written specifically for the new generation of independent and conservative thinkers.
Read more »
Surveys sending mixed signals about who should win the election: GallupGallup says its survey data is sending mixed signals about the outcome of this incredibly close race between former President Trump and Vice President Harris.
Read more »
The Bear Season 3’s Mixed Reception Addressed By FX Boss With Tantalizing Season 4 TeaseCarmy in a White Tee next to Richie in a suit from The Bear
Read more »