A history of TBI is associated with an increased risk for schizophrenia and bipolar disorder, especially in women, older adults, and those with severe head injury.
A history of traumatic brain injury is associated with a 33% increased risk for schizophrenia and a 78% increase in bipolar disorder , with the strongest link in older adults , women, and those with severe TBI , new research suggested.
The researchers identified 4184 individuals with schizophrenia and 18,681 with BD from Swedish national registries. Patients were aged ≥ 15 years at first diagnosis and born between 1973 and 1998. IRR=adjusted incidence rate ratio; BD=bipolar disorder; SCZ=schizophrenia; TBI=traumatic brain injury The association between TBI and BD was significantly stronger in women vs men, which applied to any TBI exposure and TBI sustained at different ages. However, the pattern of excess risk for women in schizophrenia was not statistically significant.
Bipolar Mania Manic Depression Bipolar Affective Disorder Traumatic Brain Injury TBI - Traumatic Brain Injury TBI Concussion Mild Traumatic Brain Injury Mild TBI MTBI Head Injury Injury To The Head Injury Schizophrenia Geriatrics Elder Care Geriatric Medicine Older Adults Seniors Senior Citizens Elderly Brain Epidemiology Match Match Day Match Application
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