Targeted vitamin D supplementation for those with low levels can reduce the risk of depression, but shows no significant impact on chronic pain or other conditions.
By Dr. Sanchari Sinha Dutta, Ph.D.Jul 7 2024 A study published in the journal Translational Psychiatry reveals that targeted vitamin D supplementation in individuals with vitamin D deficiency may reduce the risk of probable lifetime major depression.
Randomized controlled clinical trials of vitamin D supplementation in patients with chronic pain have mostly produced mixed results. In contrast, systematic reviews of randomized trials have highlighted the positive impact of vitamin D supplementation on depression, depressive symptoms, and negative emotions.
Since genetic variants are randomly distributed at conception, they are unlikely to be related to possible confounding factors. Moreover, chronic pain conditions cannot affect the genotype, nullifying the possibility of reverse causality. Related StoriesThe scientists restricted their analyses to 333,025 unrelated participants of European ancestry with a valid vitamin D measurement. They determined the causal impact of vitamin D level on four outcomes, including fibromyalgia, clinical fatigue, chronic widespread pain, and probable lifetime major depression.
Important observations The linear Mendelian randomization analyses revealed that genetically predicted levels of vitamin D are not associated with fibromyalgia, clinical fatigue, chronic widespread pain, and probable lifetime major depression. However, the study could not find any significant associations between genetically predicted vitamin D levels and fibromyalgia, clinical fatigue, chronic widespread pain, or probable lifetime major depression. This finding suggests that vitamin D supplementation is unlikely to reduce the risks of these outcomes in the population as a whole.
Vitamin D Blood Bone Chronic Chronic Pain Fatigue Fibromyalgia Genetic Inflammation Pain Psychiatry UK Biobank Vitamin D Deficiency
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Drivers using phones or not wearing seat belts targeted by AIThe mobile unit will be taken to locations in East Yorkshire and Northern Lincolnshire from 10 June.
Read more »
Barclays Bank in Preston targeted as part of nationwide actionRed paint and damage at Barclays in Preston A bank in Preston has been targeted as part of nationwide action undertaken by activists. Glass has been sha
Read more »
Police statement after Barclays branches targeted by pro-Palestine groupsCriminal damage investigations underway and five arrests made since April, said GMP
Read more »
More than 15 Barclays branches targeted by campaign groupMore than 15 branches of Barclays Bank across England and Scotland have been vandalised by a campaign group.
Read more »
FAP-targeted therapy demonstrates significant efficacy in controlling advanced sarcomasFibroblast activation protein (FAP)-targeted radioligand therapy is safe and effective for treating patients with progressive metastatic tumors, specifically advanced sarcomas, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.
Read more »
King Charles' first official portrait targeted by animal rights activistsAnimal rights activists have targeted a portrait of the King, appearing to paste over his face with the animated character Wallace.
Read more »