Targeting refractory prostatecancer: A novel radiopharmaceutical hits the bullseye osaka_univ
]. Non-radiolabeled PSMA5 and PSMA1 were also administered to LNCaP xenograft mice and compared with saline-injected mice to assess the absence of antitumor effect by the PSMA compound itself. Tumor sizes were measured using a caliper, calculated using the following elliptical sphere model equation, and compared between injected mice and controls. The body weight was also monitored.
Plasma was obtained by centrifuging a portion of the blood sample collected at the time of euthanasia and was measured using a dry clinical chemistry analyzer . Blood urea nitrogen and creatinine levels were also measured. Cre values less than 0.2 were considered 0.2 in the statistical analysis.
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