Systemic Treatment May Reduce Need for Brain Radiotherapy

Malignant Head And Neck Neoplasm News

Systemic Treatment May Reduce Need for Brain Radiotherapy
Head And Neck CancerHead And Neck Cancer (HNC)Brain Metastasis
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A significant minority of patients with brain metastases may avoid radiotherapy, but they need to be carefully selected.

BARCELONA — The oncologist's goal is to provide cancer patients with the most effective and least toxic treatment available. For patients withAt the European Society for Medical Oncology Congress, Anna Sophie Berghoff, MD, PhD, head of the Central Nervous System Tumor Unit at the Medical University of Vienna in Austria, said that neurotoxic side effects can be avoided in some patients by using systemic treatment as a first-line therapy.

"There were fears that a molecule the size of T-DXd would be too large to cross the blood-brain barrier and would not treat brain metastases," he added."But the results have shown positive outcomes for patients with brain metastases.". Systemic treatments are also significantly more effective in newly diagnosed patients with brain metastases compared with those who have recurrent brain metastases.

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