Synthetic antibody could prevent and treat COVID-19 AakADoctor healthcaremagic dailyhealthtips
In an effort to trick the virus, the researchers behind the study designed a “decoy” ACE2, which the virus recognizes in the same way it does the real thing. However, it is not attached to cells in the body.
All of the antibodies worked against SARS-CoV-2, but one, called MDR504, was particularly effective. The virus bound more tightly to this particular antibody than it does to the natural ACE2 in the body. “Unlike other agents in development against the virus, this protein is engineered to go to the lungs to neutralize the virus before it can infect lung cells.”What is more, the antibody remained in the system for a long time. After 6 days, half of what the researchers injected was still in circulation in the mice.The researchers also say that the antibody could be dual purpose; they could use it to prevent infection and as a treatment for COVID-19.
However, because it also has a long half-life, these injections could be relatively infrequent, the researchers suggest.
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