Switching to High-Sensitivity Troponin Tests Cuts Death Risk in ACS Patients

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Switching to High-Sensitivity Troponin Tests Cuts Death Risk in ACS Patients
CARDIAC HEALTHEMERGENCY MEDICINETRPONIN ASSAYS
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A study in Australia found that using high-sensitivity cardiac troponin I assays in emergency departments was linked to a reduction in both one-year mortality and new admissions for myocardial infarction (MI) in patients with suspected acute coronary syndrome (ACS).

Switching from a conventional to a high-sensitivity cardiac troponin I assay in emergency departments is associated with a reduction in both mortality at 1 year and new admissions for myocardial infarction in patients presenting with suspected acute coronary syndrome .Researchers compared outcomes between hospitals using high-sensitivity cardiac troponin and conventional assays in a retrospective study across nine tertiary hospitals in Australia.

The study period was divided into a preperiod, during which hospitals used conventional assays , and a postperiod, during which they shifted to high-sensitivity assays . The primary outcome was all-cause death at 1 year; secondary outcomes included all-cause death at 30 days, new MI admissions, and a composite of death/new MI cases at 30 days and 1 year.Switching from conventional to high-sensitivity cardiac troponin I assays in the postperiod was associated with a 10% lower risk for death and a 12% lower risk for death/new MI at 1 year.

The switch to high-sensitivity assays was associated with a 13% reduction in the risk for death and a 14% reduction in the risk for the composite outcome of death/new MI at 30 days.

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CARDIAC HEALTH EMERGENCY MEDICINE TRPONIN ASSAYS MYOCARDIAL INFARCTION ACUTE CORONARY SYNDROME

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