Swapping Salt for a Substitute May Reduce Risk of Heart Attack or Stroke, Research Finds
from China which found salt substitutes were able to decrease the risk of heart attacks, stroke, and early death. But scientists wondered if this result could be considered a worldwide result, or tied to China specifically.
To test this, researchers used the SSaSS study and additional clinical trials published up to August 2021 to determine the effects of salt substitutes on heart health on a worldwide scale. For this analysis, they used data from 21 relevant studies that spanned nearly 32,000 people from Europe, the Western Pacific Region, the Americas, and South-East Asia.
The final data found that salt substitutes were able to lower blood pressure in all participants regardless of geography, age, sex, history of high blood pressure, weight, baseline blood pressure, or baseline levels of urinary sodium and potassium. Overall, the reduction in systolic blood pressure was 4.61 mmHg, and the reduction in diastolic blood pressure was 1.61 mmHg.
In the studies used, the salt substitutes contained sodium chloride and potassium chloride. The proportions of sodium chloride in the salt substitutes varied from 33% to 75% and potassium ranged from 25% and 65%. For each 10% lower proportion of sodium chloride in the salt substitute, systolic blood pressure dropped 1.53 mmHg and diastolic blood pressure dropped 0.95 mmHg.
Additionally, data pulled from five of these trials that included more than 24,000 participants found that salt substitutes lowered the risk of early death from any cause by 11%, from cardiovascular disease by 13%, and the risk of heart attack or stroke by 11%.Salt substitutes are an option people can use to help lower blood pressure. Many salt substitutes , called
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