The growing number of breast cancer survivors highlights the need for holistic and coordinated survivorship care to help women deal with a myriad of issues.
Advances in breast cancer detection and treatment over the past decades have led to an increase in the number of women diagnosed at earlier stages and successfully treated, ushering in a new era of survivorship.
The challenges following breast cancer diagnosis and treatment can be both visible and invisible, said Brown, a patient advocate and member of the Breast Cancer Working Group at the University of Alabama at Birmingham, Alabama. Cancer treatment is also costly, leading to financial toxicity for many patients, which also"affects adherence to treatment and overall family well-being," Brown explained. Survivors may struggle to access financial assistance due to complex eligibility requirements and a lack of awareness about available resources.
Several clinical trials conducted from the late 1980s to the early 2000s showed no survival benefit from intensive surveillance strategies, including imaging and laboratory tests, compared to routine clinical follow-up. Some studies even demonstrated a trend toward harm, given the number of false positives.
He cautioned, however, that while sensitive ctDNA tests exist and have clinical validity in identifying minimal residual disease,"their clinical utility has not yet been demonstrated," Cescon said, adding that any surveillance strategy must consider the psychological effect of frequent testing and the potential for false positives or negatives.
Malignant Breast Neoplasm Breast Carcinoma Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Cancer Survivor Liquid Biopsy Fluid Biopsy Fluid Phase Biopsy Cancer Blood Test Cancer Saliva Test Blood Biopsy Serum Biopsy Breast Mammary Gland Toxicology Toxicity Poisoning Toxins Breast Pain Quality Of Life QOL Health Related Quality Of Life
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