'Our hope is that these findings provide additional data to support Mohs as the standard of care for primary surgical treatment of high-stage cSCC,' the study's lead author said.
PHOENIX — Mohs surgery appears to be superior to wide local excision in patients with high-stage cutaneous squamous cell carcinoma , according to findings from a retrospective study. The benefit was seen across all outcome measures, including rates of recurrence, metastasis, and mortality.
Although patients diagnosed with cSCC usually have good outcomes, high-stage disease is associated with a higher risk for recurrence, metastasis, and death. Both Mohs surgery and WLE are used to treat cSCC, but a comparison of outcomes has not been well established in the setting of high-stage cSCC.
They found that overall, the risk for all adverse outcomes was lower among patients who had undergone Mohs surgery than among those treated with WLE, with the following results: Rates of local recurrence . "There is no benefit to a standard excision over Mohs," Rohrer emphasized."If a surgeon is not sure if they have attained clear margins, they could and often do take a little more tissue to be certain."
Prather also pointed out that there are circumstances when WLE may be a more suitable treatment."Mohs is not very good if there is bony involvement," he said."This most often happens when the lesion is on the scalp and has invaded the skull. WLE may still be the preferred choice."
Malignant Skin Neoplasm Mohs Surgery Mohs Micrographic Surgery Surgery Metastasis Metastatic Carcinoma Metastatic Cancer Metastases Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Distant Metastasis Distant Metastases Squamous Carcinoma Squamous Cancer Squamous Cell Carcinoma Tumor Electronic Health Records Electronic Health Record EHR Electronic Medical Record
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