Summit's computing power helped researchers analyze data from over half a million veterans to uncover links between genes and disease.
ORNL’s summit supercomputer, set to be decommissioned by the end of the year, added another chapter to its legacy in high-performance computing and scientific research.in July, researchers harnessed the computing power of Summit to analyze genetic data from over half a million U.S. veterans, marking one of the most extensive and diverse genome-wide association studies to date.
Notably, 29% of the MVP’s cohort includes individuals genetically similar to African, Admixed American, and East Asian ancestries, addressing the critical gap in genetic research that predominantly focuses on individuals of European descent. The original VA data was designed for analysis on CPU-based systems and had to go through a significant transformation to get optimized for thepowering Summit. This conversion process took several years and involved figuring out calculations that explore associations between genetic markers and health traits without compromising accuracy.
David Heise, an ORNL software engineer and pipeline team leader, aimed to make the data “accessible at a high level in an easily accessible way,” ensuring that the broad scientific community could leverage the information without compromising individual privacy as the visualizations contain only summary statistics.
Data Center Genetic Studies Research Summit Supercomputer
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