Pulsed field ablation (PFA) is safe for treating patients with common types of atrial fibrillation (AF), according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.
Mount Sinai Health SystemJul 8 2024 Pulsed field ablation is safe for treating patients with common types of atrial fibrillation , according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.
MANIEFST-17K provides confidence that, unlike conventional thermal ablation, PFA with the pentaspline catheter does not cause the most feared complication of AF ablation-;esophageal damage-;nor does it cause pulmonary vein stenosis or persistent injury to the diaphragm. This study found that other general complications were also rare, including pericardial tamponade occurring in approximately one in 200 patients, stroke in one in 1,000, and death in even less than one in 1,000 patients.
AF is an irregular heartbeat or heart rhythm disorder; 2.7 million Americans live with some form of it. Patients with AF can undergo a catheter procedure, called catheter ablation, to treat this abnormal heart rhythm. This procedure involves making scars in small areas in the heart involved in the abnormal rhythm, which prevents abnormal electrical signals or rhythms from moving through the heart.
Related StoriesThis retrospective, observational study analyzed 17,642 patients with paroxysmal and persistent AF after undergoing PFA procedures at 106 centers in 2021. Procedures were performed with pentaspline PFA catheter, the most commonly used PFA catheter worldwide. Researchers found no energy-specific complications among patients, including no esophageal damage, pulmonary vein stenosis, or persistent phrenic nerve injury.
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Pulsed field ablation procedures found safe and effective for atrial fibrillation patientsPulsed field ablation (PFA) is safe for treating patients with common types of atrial fibrillation (AF), according to the largest study of its kind on this new technology, led by the Icahn School of Medicine at Mount Sinai.
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