Inulin-propionate ester wasn't more effective than inulin in preventing weight gain over 12 months in young adults at risk for obesity, showed a clinical trial of the fiber-mimicking compound.
In young adults with overweight, inulin-propionate ester , a novel food ingredient that aims to mimic the beneficial role of dietary fiber by boosting production of short-chain fatty acids in the colon, does not appear as effective in preventing weight gain as it does in middle-aged adults with overweight, finds a randomized clinical trial.High-fiber diets are associated with lower weight gain , perhaps due to increased proportionate stimulated in the colon.
The participants were recruited between July 2019 and October 2021 and randomly assigned to receive 10 g of either IPE or inulin once daily for 12 months while maintaining their existing diet and exercise routines. Fat-free mass increased in the IPE group by 1.07 kg , while fasting glucose levels were elevated by 0.11 mmol/L , though within normal ranges.
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