Study reveals neural mechanism of light-promoted early brain development of mammals CellCellPress
The research team led by Prof. Xue Tian and Bao Jin from the Department of Life Science and Medicine at the University of Science and Technology of China of Chinese Academy of Sciences identified the neural mechanism and lifelong effect of light-promoted early brain development in mammals. The results were published inVisual perception begins with the retina.
In this study, the researchers first found that compared to control pups , neonatal mice lacking the photosensitivity of ipRGCs had reduced frequency of mini-excitatory postsynaptic currents and number of dendritic spines of pyramidal neurons in multiple sensory cortex and hippocampus, while those deficits of synaptogenesis were observed in another experimental group reared in the dark from birth.
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