Overweight and obese adults using popular diabetes medications to suppress their appetites are 'significantly more likely' to shed pounds with Eli Lilly's Mounjaro than with Novo Nordisk's Ozempic, a new study has found, a result that could have major implications for one of the hottest new markets in the pharmaceutical field.
The injectable drug Ozempic is shown Saturday, July 1, 2023, in Houston.
Tricia Rodriguez, the study’s lead author, said its findings confirm earlier placebo-controlled trials that found tirzepatide, the primary active ingredient in Mounjaro, is more effective for weight loss than Ozempic’s key ingredient, semaglitude. She said further research is needed to explain why. With that in mind, the researchers noted a “high rate of discontinuation” from those taking the drubs, with 55.9% of Mounjaro patients and 52.5% of Ozempic patients quitting within a year.
The FDA approved Mounjaro for Type 2 diabetes in 2022. After Indianapolis-based pharmacy giant Eli Lilly & Co. reported an explosion in sales, the FDA approved a version called Zepbound for weight loss in November.In recent months, some pharmacies and clinics have started producing compounded versions of Ozempic and Mounjaro to capitalize on the absence of affordable generic versions.
Mr. Means, a former lobbyist for the food and pharmacy industries, has argued that the drugs offer companies a way of profiting from obesity for years without curing it.
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