A recent study published in the Journal of the American Medical Association has found that breast cancer patients with high levels of tumor-infiltrating lymphocytes (TILs) have a better prognosis. The study aimed to explore whether patients with a favorable prognosis can avoid intensive chemotherapy regimens. Researchers followed patients for an average of 18 years and found that five years after surgery, 95% of patients with high TIL levels were still alive, compared to 82% of patients with low TIL levels. The recurrence rate for breast cancer was also significantly lower among those with high TIL levels.
Journal of the American Medical Association.to explore whether patients with a favorable prognosis can avoid intensive chemotherapy regimens," said lead researcher Dr. Roberto Leon-Ferre, aare more likely to grow rapidly and spread to other parts of the body, and also are more likely to recur following treatment, researchers said in background notes.
However, until now no one has thought to examine whether TILs could be used to help doctors better plan a patient's cancer," said co-senior study author Dr. Matthew Goetz, an oncologist at Mayo Clinic Comprehensive Cancer Center.. These patients were followed for an average of 18 years. Five years after surgery, 95% of patients with high TIL levels were still alive, compared to 82% of patients whose tumors had low TIL levels, researchers found. Further, the recurrence rate for breast cancer was significantly lower among those with high TIL levels, results sho
Breast Cancer Tumor-Infiltrating Lymphocytes TIL Levels Prognosis Chemotherapy
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