An analysis of 10 years of health data showed that risk factors for needing mechanical ventilation changed for patients with newly diagnosed sepsis as more time passed after onset.
In the study, 13.5% of patients with a new diagnosis of sepsis required initiation of mechanical ventilation. More than half of these patients required mechanical ventilation within the first 24 hours after sepsis onset, while initiation of mechanical ventilation occurred after 24 hours in 47.4% of patients.
with sepsis who were not receiving mechanical ventilation at sepsis onset. The study is published in theCo-author Robert Freundlich, MD, MS, MSCI, is an associate professor, department of anesthesiology, and chief of the anesthesiology informatics research division at Vanderbilt University Medical Center, Nashville, Tennessee.
Of all eligible patients, 3,891 required mechanical ventilation within 30 days after sepsis onset. Of these, 2,046 required mechanical ventilation within 24 hours of diagnosis. Mechanical ventilation was subsequently initiated for 441 patients from one to two days after sepsis onset, and for 312 patients from two to three days following diagnosis. The remaining 1,092 experienced late respiratory failure or required mechanical ventilation three to 30 days after diagnosis.
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