The findings contrast with the expectation that increased systemic inflammation in moderate to severe AD would correspond with a higher incidence of MACE, said Bunick.
Patients with atopic dermatitis had a lower risk for major adverse cardiovascular events than the general population, and this risk was significantly lower than that of patients with rheumatoid arthritis , according to an analysis of
Patients were classified as having moderate to severe disease if they received dupilumab for AD or advanced systemic therapy for RA at any time during the follow-up period. The matched moderate to severe AD and non-AD cohorts were composed of 7134 patients each. The incidence of MACE was defined as inpatient hospitalization with myocardial infarction or stroke.
Another unexpected result, he said, was that among patients with moderate to severe AD, the risk for MACE was not significantly different from that of non-AD matched controls, suggesting that the inflammatory burden in AD might not translate to as high a cardiovascular risk as previously assumed.for MACE based on a study of another JAK inhibitor in patients with RA, but"this may not apply to AD because patients with AD have a lower risk for MACE.
Match Match Day Match Application Medical Students Match Medical Life Physician Lifestyle Medical Lifestyle Resident Lifestyle Medical Student Lifestyle Nurse Lifestyle Atopic Dermatitis Atopic Eczema CV Risk Cardiovascular Risk CV Risk Factors Cardiovascular Risk Factors Cardiovascular Risk Management Rheumatoid Arthritis RA - Rheumatoid Arthritis
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