Children with refractory systemic juvenile idiopathic arthritis–related lung disease had complete remission after stem cell transplantation.
Stem cell transplantation tames some refractory systemic juvenile idiopathic arthritis–related lung disease that does not respond to other treatment.Retrospective cohort study of 13 children with refractory systemic juvenile idiopathic arthritis–related lung disease who had allogeneic hematopoietic stem cell transplant ation .
Outcomes included transplant-related complications, pulmonary outcomes , and overall outcomes .Five patients developed acute graft vs host disease of varying grades, but none experienced chronic disease. Four patients died from complications including cytomegalovirus pneumonitis , intracranial hemorrhage , and progressive sJIA-LD .
Hematopoietic Stem Cell Transplant Stem Cell Transplantation Stem Cell Therapy Haematopoietic Stem Cell Transplant Hematopoietic Stem Cell Transplantation (HSCT) Haematopoietic Stem Cell Transplantation (HSCT) Stem Cell Research And Therapy Transplantation Of Stem Cells Transplantation Of Hematopoietic Stem Cells Stem Cell HSCT Cell Transplantation
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