Daily News | Spark Therapeutics, the heart of Philly’s gene therapy surge, has announced CEO change
CHOP made the first venture capital investments in Spark and netted the hospital more than $750 million, according to Marrazzo.“My goal was to help the company transition into Roche and position it to take full advantage of what we thought Roche could provide, which is the support, investment, and long-term orientation that would allow us to grow our investment in research and development and the science,” Marrazzo said. “We’re at that point now.
Spark employs 800 and is poised to have an even bigger presence in Philadelphia. In December, the company announced plans, at 30th and Chestnut Streets. Construction is expected to begin later this year. Philip, 48, a Drexel University graduate, said Spark has developed a robust pipeline of potential gene therapies that could be manufactured in the new facility. A treatment for hemophilia is furthest along in clinical trials, Philip said. Also in clinical trials is a treatment for Pompe disease, a metabolic disorder that damages muscle and nerve cells., that was described during a December investment call as setting a “high bar” for competitors like the potential gene therapy cure at Spark.
“Not every treatment works for every patient. Multiple options are always necessary and Roche is a company that always looks at diseases pretty broadly,” Philip said. “They want to have obviously the most benefit for patients possible. if that means multiple products, so be it.
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