Two of the anti-inflammatory drugs prescribed to relieve back pain may block healing of the injury and so cause worse pain long term
at McGill University in Montreal and her colleagues investigated 98 people who had recently developed lower back pain. The researchers took regular blood samples and analysed them to see which genes were active in the immune cells circulating in the blood.In those whose pain subsided over the next three months, one type of inflammatory immune cell – the neutrophils – showed higher levels of activity than in people whose pain persisted.
“Inflammation is painful, but this inflammation is needed for our body to resolve pain,” says Diatchenko. “Pain resolution is an active process that requires neutrophil activation.”
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