Researchers conducted a single-center cohort study of more than 47,000 patients diagnosed with CRC from January 1, 1973, to March 1, 2023.
Socioeconomic status contributes to 29% of racial disparities in colorectal cancer survival, with molecular factors accounting for 10%. Black patients have worse overall survival than White patients, whereas Asian and Hispanic patients have better outcomes.Researchers conducted a single-center cohort study at a tertiary-level cancer center, including 47,178 patients diagnosed with colorectal cancer from January 1, 1973, to March 1, 2023.
Analysis included mediation analysis with sequential multivariate Cox regression models to determine the relative contribution of variables to survival disparity. Patients' demographic characteristics and clinical and molecular data were collected from electronic health records and a cancer registry.TAKEAWAY:"Our single-institution study is an important complement to large multi-institution registry studies in which cancer stage at diagnosis has been observed to be the major contributor to survival disparity.
This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.
Colorectal Cancer (CRC) Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Social Determinants Of Health SDOH Social Determinants Of Health (SDOH) Genomics Genomic Medicine Socioeconomics Racial Disparity Ethnic Disparity Racial-Ethnic Disparity Racial-Ethnic Disparities Texas Artificial Intelligence Deep Learning AI NPL Machine Learning
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