Sinovac's two-dose COVID-19 vaccine followed by a booster Pfizer-BioNTech shot showed a lower immune response against the Omicron variant compared with other strains, according to a study by researchers.
shot produced an antibody response similar to a two-dose mRNA vaccine, according to the study. Antibody levels against Omicron were 6.3-fold lower when compared with the ancestral variant and 2.7-fold lower when compared with Delta.on Twitter that CoronaVac recipients may need two additional booster doses to achieve protective levels needed against Omicron.
The two-dose Sinovac vaccine alone did not show any detectable neutralization against Omicron, according to the study that analysed plasma samples from 101 participants in the Dominican Republic. A study from Hong Kong last week said that even three doses of the Sinovac vaccine did not produce enough antibody response against Omicron and that it had to be boosted by a Pfizer-BioNTech shot to achieve "protective levels."
Sinovac's CoronaVac and state-owned Sinopharm's BBIBP-CorV vaccine are the two most-used vaccines in China and the leading COVID-19 shots exported by the country. Hong Kong has been using the Sinovac and Pfizer-BioNTech vaccines.Reporting by Jose Joseph and Shubham Kalia in Bengaluru; Editing by Ramakrishnan M.Subscribe for our daily curated newsletter to receive the latest exclusive Reuters coverage delivered to your inbox.
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