Inductively coupled plasma mass spectrometry (ICP-MS) is prominently used for analyzing elemental composition in individual cells. However, the conventional sample introduction system of ICP-MS causes damage to large mammalian cells.
Inductively coupled plasma mass spectrometry is prominently used for analyzing elemental composition in individual cells. However, the conventional sample introduction system of ICP-MS causes damage to large mammalian cells. Now, researchers suggest an efficient method of introducing mammalian cells using a microdroplet generator that maintains the cell's structure without compromising elemental composition. These findings can open new avenues for the diagnosis and prognosis of diseases.
Although the transport efficiency of traditional scICP-MS analysis using a nebulizer reaches 10% for yeast cells, it cannot be used for mammalian cells owing to their fragile nature. Chemical fixation is known to enhance the strength of mammalian cells, but it greatly affects the elemental contents, leading to inaccuracy of the analysis. There is thus a need to develop a sample introduction system that does not cause any damage to the mammalian cells.
The researchers found that the cell transport efficiency increased drastically with the use of µDG. Moreover, they also estimated magnesium, iron, phosphorus, sulfur, and zinc in the K562 cells and found that µDG maintained the cell's original structure in contrast to the conventional system that usually alters the cell's structure.
Immune System Lymphoma Brain Tumor Nervous System Cancer Lung Cancer Medical Topics
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Single Women Happier Than Single Men, Research FindsA recent study has revealed that single women are significantly happier with their relationship status compared to single men. This finding challenges traditional stereotypes and may be attributed to evolving societal norms.
Read more »
Cedar Ridge's New American Single Malt Whiskey Is Finished in Wine BarrelsCedar Ridge Distillery has released a new American single malt whiskey called the QuintEssential: Wine Club, First Meeting. This unique whiskey is finished in barrels previously used to mature different types of wine, including amontillado sherry, tokaji, moscatel, and Pinot Noir.
Read more »
Saquon Barkley to Sit Out, Missing Chance at Single-Season Rushing RecordPhiladelphia Eagles running back Saquon Barkley is expected to sit out the team's final regular-season game, forgoing an opportunity to break Eric Dickerson's NFL single-season rushing record. Barkley needs 101 yards to surpass Dickerson's 2,105-yard mark set in 1984. The Eagles have already clinched a playoff berth, prioritizing player rest and health ahead of a potential Super Bowl run.
Read more »
Saquon Barkley Expresses Disappointment Over Missing Single-Season Rushing RecordPhiladelphia Eagles running back Saquon Barkley expressed disappointment after being rested in the final game of the season, preventing him from potentially breaking the NFL single-season rushing record.
Read more »
Future nurse, football star, single mother, father of 2 killed in New Orleans attackOfficials have not yet released the names of the 15 people killed in the New Orleans New Year's Day truck attack, but their families and friends have started…
Read more »
An aspiring nurse, football star, single mother and father of 2 killed in New Orleans attackNEW ORLEANS (AP) — An 18-year-old girl dreaming of becoming a nurse, a single mother, a father of two and a former Princeton football star suffered fatal injuries when the driver of a white p…
Read more »