Singapore scientists to start human trials of COVID-19 vaccine in August

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Singapore scientists to start human trials of COVID-19 vaccine in August
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Singapore scientists testing a COVID-19 vaccine from U.S. firm Arcturus Therapeutics plan to start human trials in August after promising initial ...

SINGAPORE: Singapore scientists testing a COVID-19 vaccine from US firm Arcturus Therapeutics plan to start human trials in August after promising initial responses in mice.

More than 100 vaccines are being developed globally, including several already in human trials from the likes of AstraZeneca and Pfizer to try and control a disease that has infected more than 8 million people and killed over 430,000 worldwide.The vaccine being evaluated by Singapore's Duke-NUS Medical School works on the relatively-untested Messenger RNA technology, which instructs human cells to make specific coronavirus proteins that produce an immune response.

"The fact that it replicates and triggers a very balanced immune response, both in terms of the antibody and killer cells - those are welcome properties," Ooi Eng Eong, deputy director of the school's emerging infectious diseases programme, told Reuters on Tuesday . Antibodies stick to the virus and prevent it from infecting cells, while killer cells, another arm of the immune system, recognise infected cells and destroy them, he said.

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