Short-Course Vasoconstrictors After EVL: Time for a New Standard of Care?

Biliary Disease News

Short-Course Vasoconstrictors After EVL: Time for a New Standard of Care?
Gallbladder DiseasePatient SafetyClinical Guidelines
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New research challenges the traditional practice of continuing vasoconstrictor therapy for 5 days after endoscopic variceal ligation for acute variceal bleeding.

PHILADELPHIA — New research challenges the traditional practice of continuing vasoconstrictor therapy for 5 days after endoscopic variceal ligation for acute variceal bleeding , finding that a shorter course of 1-3 days may suffice, without raising the risk for rebleeding, if the initial ligation successfully controls bleeding.

Commenting on this research, Nancy Reau, MD, of Rush University in Chicago, said, “We should always question the standard of care.” The study team assessed comparative outcomes based on the duration of vasoconstrictors after EVL for acute variceal bleeding in a systematic review and network meta-analysis of 11 randomized controlled trials.

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