Shocking Study Finds Severe COVID-19 Linked With Molecular Signatures of Brain Aging

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Shocking Study Finds Severe COVID-19 Linked With Molecular Signatures of Brain Aging
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Scientists emphasize the value of neurological follow-up in recovered individuals. It's true that COVID-19 is primarily a respiratory disease. However, neurological symptoms have been described in many COVID-19 patients, including in recovered individuals. In fact, a range of symptoms has been re

CDC Data as of December 9, 2022.

Mavrikaki and colleagues analyzed a total of 54 postmortem human frontal cortex tissue samples from adults 22 to 85 years old. Of these, 21 samples were from severe COVID-19 patients and one from an asymptomatic COVID-19 patient who died. These samples were age- and sex-matched to uninfected controls with no history of neurological or psychiatric disease.

“Given these findings, we advocate for neurological follow-up of recovered COVID-19 patients,” said senior and co-corresponding author Frank Slack, PhD, director of the Institute for RNA Medicine at BIDMC and the Shields Warren Mallinckrodt Professor of Medical Research at Harvard Medical School.

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