Severe irritability in children and teens: A new understanding

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Severe irritability in children and teens: A new understanding
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Kids with disruptive mood dysregulation disorder have explosive outbursts well past toddler age. Scientists are trying to work out the causes and what treatments help.

ArticleBody:This article was originally featured on Knowable Magazine. It wasn’t until her daughter entered preschool that Holly Provan, a nurse in Los Angeles, began to worry. Compared to other kids, including her younger sister, Anna had a harder time coping when something wasn’t going her way. When told to stop coloring or to leave the playground, she’d respond with explosive tantrums.

Though irritable and non-irritable kids reported similar levels of frustration, the brains of irritable children responded differently: They showed heightened activity in the striatum, a brain region important for processing rewards, as well as in the prefrontal cortex, key to regulating emotions and executing tasks. Some other studies have also hinted at unusual activity in the emotion-processing amygdala in frustrated kids, though Tseng’s study didn’t observe this.

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