Self-assembling proteins can store cellular 'memories' MIT NatureBiotech
, we need to observe physiological events over time in these large cell populations."
The researchers designed a genetically encoded system in which one of these subunits is continuously produced inside cells, while the other is generated only when a specific event occurs. Each subunit also contains a very short peptide called an epitope tag—in this case, the researchers chose tags called HA and V5. Each of these tags can bind to a different fluorescent antibody, making it easy to visualize the tags later on and determine the sequence of the protein subunits.
"We're hoping to use this kind of protein self-assembly to record activity in every single cell," Linghu says."It's not only a snapshot in time, but also records past history, just like how tree rings can permanently store information over time as the wood grows."In this study, the researchers first used their system to record activation of c-fos in neurons growing in a lab dish.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Learning to Self-Manage Abortions Is Key in a Post-“Roe” SocietyAs we head into 2023, we face the collective challenge of working to normalize knowledge of self-managed abortions.
Read more »
Trump's favorite newspaper warns GOP on verge of 'massive' self-sabotage'Republicans have a unique talent for snatching defeat from the jaws of victory,' the New York Post warned. 'They should not exercise it here.'
Read more »
The absurdity of gender self-identificationThe transgender Canadian teacher who shocked the world while wearing Z-size prosthetic breasts in the classroom is in the news again.
Read more »
Appreciating the Orgasm as an Act of Self-CareExperts explain how regular orgasms can have a positive impact on pelvic health, emotional well-being, and even skin aging.
Read more »
Police instructor shoots self in leg at New Orleans training academy firing rangeThe officer is retired with more than 30 years of service and a reserve sergeant currently assigned to the training academy as an instructor, a spokesman said.
Read more »