Science, Space and Technology News 2024
The MoTrPAC study, spanning eight years and involving 2,600 volunteers, aims to map the molecular changes caused by exercise and their health impacts, emphasizing personalized exercise recommendations based on recent findings. Credit: SciTechDaily.com
Initial findings from MoTrPAC underscore the importance of including both sexes in exercise research to fully understand its health implications, advocating for diverse representation in future studies. Gender differences were observed in molecular responses across various tissues, particularly in white fat tissue, suggesting implications for personalized exercise recommendations, especially in conditions like obesity.
Recipients of the grant worked as a consortium to develop plans for recruitment into the clinical trial portion of MoTrPAC, identification of methods to analyze tissue samples, and selection of animal models to best replicate human studies. Animal models allowed researchers to search for changes in tissues not easily accessible in human patients, such as the brain, lungs, and kidneys.
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