Tim Andrews, 66, from New Hampshire, becomes the second person to successfully receive a gene-edited pig kidney transplant. The surgery, conducted at Mass General Brigham, marks a significant advancement in the field of xenotransplantation and offers hope for addressing the shortage of human organs.
Mass General Brigham has announced the successful completion of another gene-edited pig kidney transplant , marking the first of a three-person pilot study. Tim Andrews , a 66-year-old man from Concord, New Hampshire, is the second known individual living with a pig kidney. Andrews, who had been battling kidney failure for two years and facing a lengthy wait for a human organ, is now free from dialysis. He left the hospital a week after the January 25th transplant and is recovering well.
This milestone comes at a pivotal moment in the quest to explore the potential of animal-to-human transplants as a solution to the critical shortage of human organs. Previous pig organ transplants, including two hearts and two kidneys, had limited lifespans. However, the fifth recipient, an Alabama woman, has defied expectations, thriving for over two and a half months after receiving a pig kidney transplant at NYU Langone Health in November. Building on this encouraging progress, doctors at Mass General Brigham, with FDA permission, are conducting a pilot study involving two additional pig kidney transplants. The genetically modified pig kidneys are supplied by biotech company eGenesis. United Therapeutics, another developer of gene-edited pig organs, has also received FDA approval for the world's first clinical trial of xenotransplantation. This trial will initially involve six patients receiving pig kidneys. If they experience successful outcomes over six months, the study could expand to include up to 50 additional patients. Andrews' surgery, led by Dr. Tatsuo Kawai, represents a significant step forward in this pioneering field. Kawai, who also oversaw the world's first pig kidney transplant last year, expressed optimism about the potential for long-term kidney survival. He acknowledged the uncharted territory of xenotransplantation but emphasized the valuable lessons learned from animal research and previous human attempts. Andrews' journey exemplifies the hope and resilience of patients seeking innovative solutions to end-stage organ failure. His commitment to improving his health to qualify for the pilot study underscores the extraordinary lengths individuals are willing to go to for a chance at a healthier future
Xenotransplantation Pig Kidney Transplant Organ Shortage Mass General Brigham Tim Andrews
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Man Becomes Second Known Person to Live With a Pig KidneyTim Andrews, a 66-year-old man from New Hampshire, has successfully received a genetically-edited pig kidney transplant at Massachusetts General Hospital. This marks a significant advancement in xenotransplantation, offering hope to those awaiting human organ transplants.
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New Hampshire man is second person known to be living with a pig kidneyMass General Brigham has announced the successful completion of another gene-edited pig kidney transplant, the first of a three-person pilot study.
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