Science, Space and Technology News 2024
Researchers are exploring how opioids affect the brain, with recent discoveries challenging existing beliefs about their mechanisms. New findings suggest potential new targets for treating addiction and developing nonaddictive painkillers.
“This is potentially a nondopaminergic mechanism for opioid reward, which is something people have been looking for a long time,” said Smith. For decades, many addiction researchers have primarily focused on studying four parts of the brain: the extended amygdala, the ventral tegmental area, the nucleus accumbens, and the prefrontal cortex.
“When I found out that it was in the prefrontal cortex, which is part of the brain I’ve looked at thousands of times, I was very surprised,” shared Smith. “I couldn’t believe I never noticed that.”
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