Scientists Transplant Human Tissue into Rat Brains, Opening Door to New Research

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Scientists Transplant Human Tissue into Rat Brains, Opening Door to New Research
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Scientists have transplanted human brain cells into rats. The technique could help us better understand conditions like autism and schizophrenia.

Human cells fused into the brains of rats and mice could help explore causes of autism, schizophrenia

Scientists are closer to understanding how the brain works by using a tiny, flexible, needle-like probe that can measure how different areas communicate with one another. Photo: Composite/Allen Institute for Brain ScienceBioengineered human tissue transplanted into rat brains generated hybrid neural circuits that affected the animals’ behavior, researchers said, expanding a pathway for exploring brain development and the mechanics of some diseases.

Neuroscientists at Stanford University transplanted tiny blobs of neural tissue known as organoids into the brains of newborn rats. The human cells grew and made functional connections within the rat brain, generating hybrid neural circuits, the researchers said in a study published Wednesday in the journal Nature.

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